ADVANCED CLINICALS Collagen Skin Rescue Lotion, This is a favorite body, face, all-over moisturizer that promises to truly reinvigorate the skin. Simply apply a sufficient amount of lotion onto a cleansed face, neck and hands. Then, gently massage it into the skin using upward circular motions, paying special attention to the wrinkles, until fully absorbed. With continued use, you will notice softer and plumper skin.